SUMMARY
The article studies the effect of phytocomplex used during the treatment of experimental statin hepatitis model on liver enzyme activity, lipids and antioxidant protection. In the study, rats of both sexes weighing between 158-182 g included in the experiment were divided into 4 groups. The first group included 5 intact rats, the second group included 5 animals, and the third group included 15 animals in which an experimental statin hepatitis model was created. The 15 rats in which an experimental statin hepatitis model was created were divided into 3 subgroups. Of the 15 rats in which statin hepatitis was modeled, the first subgroup of group 3 animals received amvastatin for 10 days, the second subgroup for 20 days, and the third control subgroup received only saline. The study showed that the phytocomplex proposed for the treatment and prevention of experimental statin hepatitis has a beneficial effect on the morpho-functional state of the hepatobiliary system in rats at the pathogenetic level, bringing the studied enzyme activity indicators of liver damage, lipid metabolism parameters, lipid peroxidation products and antioxidant activity indices, Catalase) to the optimal level, improving their physical condition and behavioral reactions.
Keywords: experiment, statin hepatitis, phytocomplex, hepatotropic effect

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