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ANALYSIS OF COLICS (FOENICULUM VULGARE) SYRUP PREPARATION CONTAINING ESSENTIAL OILS BY GAS CHROMATOGRAPHY
Suleymanov T.A., Hajibayli T.A.


DOI: 10.61775/2413-3302.v2i32.17


ABSTRACT
Introduction. One of the important tasks facing pharmaceutical science is the search for sources of plant preparations, rich in various groups of biologically active substances the selection of biologically active substances from these sources and the creation of new medicines based on them. The aim of the study was conducting an analysis of the drug Colics (foeniculum vulgare), which contains essential oils by Gas Chromatography. Matherial and methods. Foeniculum vulgare, called fennel ordinary, is an erect, branching perennial plant, which is commonly grown in vegetable and herb gardens for its foliage and seeds, with anise-flavored, which are usually collected for culinary use. The analysis was carried out on an Agilent 7890B Gas Chromatograph and Chromatography-mass MS 5977A spectrometer. Column size 30 m*250 μm*0.25 μm brand HP-5 MS Ultra Inert. Split- the sample is divided into 20 parts, the first part is introduced into the apparatus. The initial temperature of 50°C is maintained for 2 minutes. Then, for each minute the temperature rises by 5°C and reaches 250°C and is held for 5 mi nu tes. Hexane was used as a solvent, as a carrier gas was used (He) 1.0 ml/min. Results. As a result of the analysis, 32 components were obtained. These compounds are mainly terpenoids and various oxidation products of saturated hydrocarbons. Compounds - 9, 10, 21, 22, 23, 24, 25, 27 predominate in the analyzed syrup «Colix».
Keywords: gas chromatography, Colics, essential oils


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