SIGNIFICANCE OF TISSUE INHIBITOR METALLOPROTEINASE-1 IN THE PATHOGENESIS BREAST CANCER
Gambarova S.C.
DOI: 10.61775/2413-3302.v2i32.01
ABSTRACT
Tissue metalloproteinase inhibitors (MPTIs) play an important role in the pathogenesis of breast cancer (BC).
Although recent studies have shown the dual role of MPTIs in the development of this pathology, it has been proven
that they inhibit the activity of metalloproteinases prevent invasiveness and tumor recurrence. Conducting extensive
research towards studying the antitumor effect of these protease inhibitors, especially MPTI-1, may allow the development
of new drugs for the treatment of breast cancer.
Keywords: breast cancer, metalloproteinases, tissue inhibitors of metalloproteinases
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