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HEALTH STATUS OF NEWBORNS BORN TO MOTHERS WITH CORONAVIRUS INFECTION
Mikailzade P.N., Akperova A.S., Rzaeva L.A., Dadasheva D.T., Azhdarova B.T.


DOI: 10.61775/2413-3302.v1i43.07


SUMMARY
Objective. To assess the health status of newborns born to mothers with coronavirus infection. Materials and Methods. The study included 268 pregnant women, of whom 222 (82.8%) had laboratory-confirmed SARS-CoV-2 infection. All participants underwent a comprehensive clinical, laboratory-diagnostic, and instrumental examination. The diagnosis of COVID-19 was verified using polymerase chain reaction (PCR) testing to detect SARS-CoV-2 RNA in nasopharyngeal and oropharyngeal swabs. Results. A total of 222 pregnant women infected with SARS-CoV-2 at various gestational ages were enrolled in the study. Among them, mild COVID-19 was observed in 117 (52.7%) of cases, moderate in 84 (37.8%), and severe in 21 (9.5%). Of all infected women (n=222), 76 (34.2%) delivered. During the observation period, there were 19 cases of pregnancy loss (25%), 7 cases of antenatal fetal death (9,2%), and 4 spontaneous abortions (5,3%). Among their newborns, 34 (15.3%) were preterm and 42 (18.9%) were born at term. Conclusion. The findings indicate an increased frequency of adverse perinatal outcomes among mothers infected with SARS-CoV-2. The most common clinical problems observed in newborns born to infected mothers were: intrauterine fetal hypoxia – 35.5%; perinatal hypoxic central nervous system injury – 22.4%; respiratory distress syndrome (RDS) – 6.6%; asphyxia – 5.3%; intrauterine growth restriction (IUGR) – 3.9%.
Keywords: coronavirus infection, COVID-19, pregnancy, viral infection, SARS-CoV-2


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