SUMMARY
A prospective study was conducted of 163 patients with the new coronavirus infection COVID-19 hospitalized in the clinic of the Republican Specialized Scientific and Practical Medical Center of Epidemiology, Microbiology, Infectious and Parasitic Diseases and the Samarkand Regional Specialized Medical Center for the period 2020-2022, a study of the factor level was conducted vascular endothelial growth (VEGF A) in blood serum by enzyme immunoassay. Our studies have shown that the value of the marker of endothelial dysfunction, vascular endothelial growth factor VEGF-A, is related to gender, age, severity, and also depending on concomitant diseases. At the same time, monitoring indicators of inflammatory markers, endothelial dysfunction of the vascular endothelial growth factor VEGF-A are significant for identifying risk factors for the development of complications in cardiovascular diseases, both at the time of admission and in the period of early convalescence.
Keywords: COVID 19, comorbidity, vascular endothelial growth factor (VEGF A), endothelial dysfunction

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