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FEATURES OF ISCHEMIC STROKE IN YOUNG, PREGNANT, AND POSTPARTUM WOMEN
Mammadova N.O.


DOI: 10.61775/2413-3302.v4i38.14


SUMMARY
Objective. The aim of the present study was to evaluate the clinical and epidemiological characteristics of ischemic stroke in young women aged 18–44, including pregnant and postpartum individuals. Materials and Methods. Based on observations conducted at the Republican Clinical Hospital during 2022–2024, a total of 70 female patients with acute ischemic stroke were included and divided into three groups: pregnant, postpartum, and non-perinatal women. Results. The findings indicated that stroke occurred at a younger age in pregnant and postpartum women and was characterized by a more severe clinical course. Among pregnant women, the occurrence of PRES (Posterior Reversible Encephalopathy Syndrome), elevated blood pressure, and higher NIHSS (National Institutes of Health Stroke Scale) scores were more frequently observed. According to the TOAST classification, the leading etiology in the perinatal period (pregnant and postpartum women) was attributed to other determined causes, whereas large artery atherosclerosis predominated in non-perinatal women. Post-stroke recovery outcomes were relatively better in postpartum women, although this difference was not statistically significant. Hyperlipidemia and cardiovascular diseases were more commonly observed in non-perinatal women. Conclusion. Pregnancy and the postpartum period should be considered important risk periods for ischemic stroke, and early diagnosis and preventive measures should be strengthened in these groups.
Keywords: ischemic stroke, young women, pregnancy, postpartum period, risk factors, localization


REFERENCES
  1. Katan M, Luft A. Global burden of stroke // Semin Neurol. 2018;38(2):208-211. doi: 10.1055/s-0038-1649503
  2. GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019 // Lancet Neurol. 2021 Oct;20(10):795-820. doi: 10.1016/S1474-4422(21)00252-0
  3. Boot E, Ekker MS, Putaala J, Kittner S, et al. Ischaemic stroke in young adults: a global perspective // J Neurol Neurosurg Psychiatry. 2020 Apr;91(4):411-417. doi: 10.1136/jnnp-2019-322424
  4. Bushnell C, McCullough LD, Awad IA, Chireau MV, et al; American Heart Association Stroke Council; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Epidemiology and Prevention; Council for High Blood Pressure Research. Guidelines for the prevention of stroke in women: a statement for healthcare professionals from the American Heart Association/American Stroke Association // Stroke. 2014 May;45(5):1545-88. doi: 10.1161/01.str.0000442009.06663
  5. Maguire JM, Little R, Jha V. Stroke in pregnancy and the puerperium // Obstetric Medicine. 2022;15(2):85-90. doi:10.1177/1753495X221088653
  6. Rajeshwari KS, Agarwal V, Satish S, Jayakumar KT. An unusual presentation of posterior reversible encephalopathy syndrome—a case report // Egypt J Neurol Psychiatry Neurosurg. 2021 Jan 7; 57:3.
  7. Farroni E, Taggiasco A, Santulli G. Peripartum cardiomyopathy: a clinical review. Vessel Plus. 2025;9:2. doi:10.20517/2574 1209.2025.15
  8. Koton S, Sang Y, Schneider ALC, Rosamond WD, et al. Trends in Stroke Incidence Rates in Older US Adults: An Update From the Atherosclerosis Risk in Communities (ARIC) Cohort Study // JAMA Neurol. 2020 Jan 1;77(1):109-113. doi: 10.1001/jamaneurol.2019.3258
  9. Hinchey J, Chaves C, Appignani B, Breen J, et al. A reversible posterior leukoencephalopathy syndrome // N Engl J Med. 1996 Feb 22;334(8):494-500. doi: 10.1056/NEJM199602223340803