| AZ | EN | RU


PHYTOTHERAPY IN PREGNANT WOMEN
Kazimova A.U.


DOI: 10.61775/2413-3302.v4i38.01


SUMMARY
Modern herbal medicine, being an alternative to drug treatment, is becoming increasingly widespread in clinical practice. Almost 80% of pregnant women in the first three months of conception, and later during pregnancy, suffer from various pathologies and syndromes. Every second woman, at the time of pregnancy, has one or another diagnosis of a chronic pathology, sometimes which poses a threat of miscarriage or termination of pregnancy, as well as a threat to the health of the mother and unborn child. Such diseases include heart rhythm disturbances, diabetes mellitus, anemia, hypertension, rheumatism, arterial hypotension, bronchial asthma, pyelonephritis, glomerulonephritis, diseases of the thyroid gland, adrenal glands, congenital and acquired heart defects, and others. Many synthetic medications have a number of contraindications during pregnancy, but pharmacotherapy and maintaining the body of a pregnant woman with chronic pathology is necessary. Herbal medicines practically do not cause side effects and can be prescribed as independent long-term treatment or in combination with other medications. However, medications, herbs and supplements should be used with extreme caution during pregnancy as they may cause harmful effects on the mother and fetus.
Keywords: pregnancy, herbal medicine, fetus, medicinal plants, effectiveness and safety


REFERENCES
  1. World Health Organization. Traditional medicine. Fact sheet Number 134. http://www.who.int/mediacentre/factsheets/fs134/en. Accessed 2003; 2 Feb 20153.
  2. Karimi A., Majlesi M. Kopaei M. Herbal versus synthetic drugs; beliefs and facts // J. Nephropharmacol.; 2015; 4(1); p. 27-30.
  3. Mendoza N., Hernández C., Cornellana M. Factors determining the use of hormonal therapy and phytotherapy in Spanish postmenopausal women // Climacteric; 2016; 19(4); p. 375-80. doi: 10.1080/13697137.2016.1183625.
  4. Радзинский В.Е., Симоновская Х.Ю. Фитотерапия в акушерстве и гинекологии // Информационный бюллетень; (Москва) Изд. 2-е, испр. идоп. - Москва: Редакция журнала Status Praesens, 2015; 16 с. ISBN 978-5-905796-67-8.
  5. Shewamene Z., Dune T., Smith C. The use of traditional medicine in maternity care among African women in Africa and the diaspora: a systematic review // BMC Complement. Altern. Med.; 2017; 17(1); p. 382-387.
  6. Newman D., Cragg G. Natural products as sources of new drugs from 1981 to 2014 // J Nat Prod.; 2016; 79(3); p. 629-661; doi: 10.1021/acs.jnatprod.5b01055.
  7. WHO guidelines on developing consumer information on proper use of traditional, complementary and alternative medicine WHO; 2016 Available from: http://apps.who.int/medicinedocs/pdf/s5525e/s5525e.pdf.
  8. Kennedy D., Lupattelli A., Koren G. et al. Herbal medicine use in pregnancy: results of a multinational study // BMC Complement Altern Med.; 2013; 13; p. 355. doi: 10.1186/ 1472-6882-13-355.
  9. Ahmed M., Hwang J., Choi S., et al. Safety classification of herbal medicines used among pregnant women in Asian countries: a systematic review // BMC Complement Altern Med.; 2017; 17(1); p. 489- 495; doi: 10.1186/s12906-017-1995-6.
  10. Rukh L., Nazar H., Usmanghani K. Efficacy of Gingocap as compared to pyridoxine in the treatment of nausea and vomiting during pregnancy // Pak. J. Pharm. Sci.; 2016; 29(6); 1937-1943.
  11. Damasceno D., Leal-Silva T., Soares T. et al. Medicinal Plants for Diabetes Treatment During Pregnancy // Curr. Med. Chem.; 2017; 24(4); p. 404-410; doi: 10.2174/09298673 23666161003122914.
  12. Afiune L., Leal-Silva T., Sinzato Y. et al. Beneficial effects of Hibiscus rosa-sinensis L. flower aqueous extract in pregnant rats with diabetes // PLoS One; 2017; 12(6); e0179785. doi: 10.1371/journal.pone.0179785.
  13. Wilkinson J. Effect of ginger tea on the fetal development of Sprague-Dawley rats // Reprod Toxicol.; 2000; 14(6); p. 507-512.
  14. Jaafari M., Fotoohi A., Razavi N. et al. Herbal medicine in pregnancy // Advanced Herbal Medicine; 2016; 2 (1); p. 54-66.
  15. Kennedy D., Lupattelli A., Koren G. et al. Herbal medicine use in pregnancy: results of a multinational study // BMC Complement Altern Med.; 2013; 13; p. 355. doi: 10.11861472-6882-13-355; doi: 10.1186/1472-6882-13-355.
  16. Rouhi-Boroujeni H., Rouhi-Boroujeni H., Gharipour M., et al. Systematic review on safety and drug interaction of herbal therapy in hyperlipidemia: a guide for internist // Acta Biomed.; 2015; 86(2); p. 130-6.
  17. Rouhi-Boroujeni H., Heidarian E., Rouhi-Boroujeni H. et al. Medicinal Plants with Multiple Effects on Cardiovascular Diseases: A Systematic Review // Curr. Pharm. Des.; 2017; 23(7); p. 999-1015; doi: 10.2174/1381612822666161021160524.
  18. Kumar D., Trivedi N., Dixit R. Evaluation of the potential effect of Allium sativum, Momordica charantia, Eugenia jambolana, Ocimum sanctum, and Psidium guajava on intestinal p-glycoprotein in rats // J. Intercult Ethnopharmacol. 2017; 6(1); p. 68-74. doi: 10.5455/jice.20160902023435.
  19. Petersen I., McCrea R., Lupattelli A. et al. Women's perception of risks of adverse fetal pregnancy outcomes: a large-scale multinational survey // BMJ Open; 2014; 5(6); e007390. doi: 10.1136/bmjopen-2014-007390.
  20. Dante G1, Bellei G, Neri I, Facchinetti F. Herbal therapies in pregnancy: what works? Curr. Opin. Obstet. Gynecol.; 2014; 26(2); p. 83-91. doi: 10.1097/GCO.00000000000 00052.
  21. Centers for Disease Control and National Birth Defects Prevention Network (NBDPN). Major Birth Defects Data from Population-Based Birth Defects Surveillance Programs in the United States, 2010-2014; Birth. Defects. Research; 2017; 109: S1-S182 http://www.nbdpn.org/current/2008pdf/ Prev. BDBroch. pdf.
  22. Mai C., Cassell C., Meyer R., et al. Birth Defects Data from Population-based Birth Defects Surveillance Programs in the United States, 2007 to 2011: Highlighting Orofacial Clefts // Birth Defects Res. A Clin. Mol. Teratol.; 2014; 100(11); p. 895-904. doi: 10.1002/bdra.23329.
  23. Sachan Anupam K., Pujari Neelkanth M. Safety Uses of Phytomedicines in Pregnancy and Pediatrics: An Overview International // Journal of Progressive Pharmacy; 2015; 1(1); p. 3-10.
  24. Shirwaikar A., Verma R. Phytotherapy-Safety aspects // Indian Journal of Natural Products and Resources; 2014; 8(1); p. 55-63.