| PHARMACOVIGILANCE MEASURES IN IMPROVING THE DRUG SAFETY SYSTEM Aghayev E.M., Suleymanov M.Y., Hasanov F.I., Marinchenko Y.V. DOI: 10.61775/2413-3302.v2i40.12
SUMMARY The Pharmacovigilance is a scientific discipline and practical field with the detection, assessment, investigation, and prevention of side effects or any other problems related to medicinal products. The aim of this manuscript is to examine the fundamentals of the legal framework for pharmacovigilance and characterize the current state of pharmacovigilance. Materials and methods. In this article have been used statistical data in the last 5 years provided by the Center of Analytical Expertise under the Ministry of Health Azerbaijan Republic, reflecting the activities of the pharmacovigilance department. Results. The Statistics of notifications medicinal products causing side events were non-linear and variable haracters, with the highest number of notifications recorded in 2019 (944) and the lowest in 2021 (183). According to ATC codes (Anatomical Therapeutic Chemical classification system), the largest number of drugs associated with adverse effects was recorded for systemic antimicrobials (2024), and the smallest for systemic hormonal drugs (16). According to the WHO Drug statistical database it follows that among suspicious drugs that cause side effects by active ingredients, anti-tuberculosis drugs occupy the first place. The dinamic of notifications and warnings of side drug reactions over the 5-year period was unstable. Have been increased the number of published educational materials on pharmacovigilance. Conclusion. A well-developed pharmacovigilance system contributes to further improvement of the results of safe, effective and reliable use of medicines. Keywords: pharmacovigilance, medicinal products, side effects REFERENCES
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